Came back from a CS 5 Roadshow and Dreamweaver CS 4 decides to go a bit wonky.

The following translators were not loaded due to errors:
Server Model SSI.htm: has configuration information that is invalid.

Fixing it with these steps (thanks to Sachin (link))

1. Close Dreamweaver, if it is already open.
2. Open this folder: “C:Documents and Settings[username]Application DataAdobeDreamweaver CS4en_USConfiguration”
3. Delete the file “WinFileCache-7A9586CB.dat“
4. Start Dreamweaver